Thank you for sharing this. The atmosphere in Penrose was dark and oppressive (in a good way!). The story felt very personal.
I played through it on a Playdate. I found a couple of minor issues, and one major crash.
An "A" button icon flashes in the lower right corner of the screen for a while once you start. I assume that's only supposed to show on the title screen, to tell you what to press to start the game, but it continues on in the bedroom and sometimes the hallway. It also reappears in the bedroom if you return there later.
In the first internal room of the mall, if you exit at the very bottom left corner, you end up on the next screen in a wall. Not a bid deal since you can move up to get out of, but you can't just move straight left.
A bigger issue is near the end. After going to the mall, catacombs, playground, etc., and speaking to the giant, you select that you want to go and appear in a straight hallway running left to right. Going to the very right end causes the Playdate to crash and reset.
Finally, an optional suggestion. Many of the choices end the game, which I think adds to their import and the emotional weight of the story. But you might want to add another dialog step, like a "are you sure," at least to the ones at the end, since it's pretty easy to select one unintentionally (I did that at the giant at the end when trying to confirm the crash and had to restart from the beginning). But that's a design choice, obviously.
Edit: on looking at the game in Pulp, looks like the crashing issue is the final tile that should invoke the end. But this works fine in the Pulp browser.
For some reason invoking "fin" on an item causes the Playdate to crash, but Pulp in the browser is fine. You can change it to a sprite tile and use "interact" instead, that works fine on actual hardware. Not sure if this is a Playdate bug or what, but the browser version of Pulp should probably do the same thing as the hardware.