Best macOS apps for creating playdate graphics?

This is sort of a companion thread to this one about iPad pixel art apps, but I'm wondering if someone can help point me towards a good app for doing monochrome pixel art on macOS.

The big feature I'm looking for is something that feels very basic, because it was in every paint app for classic Macintosh, which is the ability to paint pixel-by-pixel using a particular 8x8 pixel pattern.

I've tried at least 10 different pixel art apps for the mac (and a few for Windows too), and none of them have this feature! The two closest I found was Aseprite, which allows creating custom brushes from pixels in your image, but it doesn't let you paint pixel-by-pixel. If your pattern is, for example, 4x4 or 8x8, then it only lets you paint with brushes that are 4x4 or 8x8. As near as I can tell, there's no way to paint the pattern one pixel at a time. I'll give an honorable mention to Pixen, because they specifically added features to their app for doing Playdate graphics. But similar to Aseprite, they don't have this feature for painting patterns pixel-by-pixel (there's a tongue twister for you). It only allows tiling a pattern.

Is there anything better than running an old Macintosh painting app in an emulator?

These are all fantastic suggestions, thank you! My cup runneth over.