When launching the Simulator, if you get an error like:
PlaydateSimulator: error while loading shared libraries: libwebkit2gtk-4.0.so.37: cannot open shared object file: No such file or directory
You'll need to install libwebkit2gtk-4.1.so.0. On Bazzite, dnf isn't allowed. Unfortunately, for the life of me, I can't find in my bash history how I resolved this issue, but these forums might be a good starting point for your search:
- Libwebkit2gtk-4.0.so.37 not found on Fedora 41
- Simulator support for Ubuntu 24.04
- Issue while launching the Playdate simulator on Ubuntu 24.04 - #13 by Bubu
So sorry I can't be more help here 
apt isn't available on Bazzite either. Best of luck!